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研究发现:3株感染根管内产黑色素类杆菌、牙髓类杆菌、产黑类杆菌、中间类杆菌的内毒素脂多糖,对体外培养的人牙髓、牙周膜成纤维细胞具有细胞毒作用,其最低抑制浓度为100ug/ml,并表现出时间依赖性和浓度依赖性。
The results showed that endotoxin lipopolysaccharide of melanobacteria, pulp bacteria, bacillus amyloliquefaciens and middle bacillus in three infected endodontic tubes had cytotoxity to human dental pulp and periodontal ligament fibroblast cultured in vitro The minimum inhibitory concentration of 100ug / ml, and showed a time-dependent and concentration-dependent.