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目的探讨结核感染T细胞(TB-IGRA)检测与糖链抗原125(carbohydrate antigen 125,CA125)检测对结核性腹膜炎(tuberculosis peritonitis,TBP)的临床诊断价值。方法收集2013年10月-2014年10月就诊于新疆人民医院消化科的结核性腹膜炎患者48例,对照组38例,进行外周血TB-IGRA以及CA125检测,分析比较2种方法在临床上对结核性腹膜炎的诊断价值。结果根据统计学结果分析,TB-IGRA的灵敏度、特异度、阳性预测值、阴性预测值与CA125比较,差异均无统计学意义(P>0.05)。结论 TB-IGRA与CA125检测对TBP临床诊断价值相当,联合使用2种方法能提高对结核性腹膜炎临床诊断的可靠性。
Objective To investigate the diagnostic value of TB-IGRA and carbohydrate antigen 125 (CA125) in the diagnosis of tuberculosis peritonitis (TBP). Methods Forty-eight patients with tuberculous peritonitis who were treated in the Department of Gastroenterology of Xinjiang People’s Hospital from October 2013 to October 2014 were enrolled in this study. Thirty-eight patients in the control group were enrolled in this study. TB-IGRA and CA125 were detected in peripheral blood. Diagnostic value of tuberculous peritonitis. Results According to the statistical analysis, the sensitivity, specificity, positive predictive value and negative predictive value of TB-IGRA were not significantly different from those of CA125 (P> 0.05). Conclusion The TB-IGRA and CA125 tests are of value in the clinical diagnosis of TBP. The combined use of two methods can improve the reliability of clinical diagnosis of tuberculous peritonitis.