我们以往的研究一再发现,荷瘤小鼠在肿瘤发生后,会自发形成证候及其演变,早期以邪毒壅盛证、气虚证多见,且发现邪毒壅盛证动物预后差,带瘤生存时间短。鉴于学术界以往的研究观察到中医证候的形成与甲状腺密切相关,那么,邪毒壅盛证发生时,甲状腺是否存在独特的基因表达特征,是否 Our previous studies have repeatedly found that tumor-bearing mice spontaneously develop syndromes and their evolution after tumorigenesis. In the early stage, the drug was more effective and Qi deficiency syndrome was more common. Tumor survival time is short. In view of the academic research in the past observed the formation of TCM syndromes and thyroid are closely related, then, when the evil toxin Sheng certificate, the thyroid is there a unique gene expression characteristics, whether