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目的观察进展期胃癌患者行腹腔镜手术效果及免疫学分析结果。方法选取2011年4月-2013年8月,我院收治的进展期胃癌患者106例,以数字法随机分为观察组和对照组各53例。对照组患者进行开腹手术治疗,观察组患者行腹腔镜手术治疗,对比两组疗效并进行免疫学分析。结果观察组治疗有效率(92.45%)显著高于对照组(71.70%)。两组治疗前CD3+、CD4+水平对比差异无统计学意义(P>0.05);但治疗后均有所上升,且观察组CD3+、CD4+水平高于对照组,差异有统计学意义(均P<0.05)。结论腹腔镜胃癌根治术治疗进展期胃癌效果显著,能显著减轻患者痛苦,降低术后并发症发生率,对免疫学指标CD3+和CD4+有明显改善作用,有利于促进患者早日康复。
Objective To observe the effect of laparoscopic surgery and immunological analysis in patients with advanced gastric cancer. Methods From April 2011 to August 2013, 106 cases of advanced gastric cancer admitted to our hospital were randomly divided into observation group and control group with 53 cases in each group. Patients in the control group underwent laparotomy. Patients in the observation group underwent laparoscopic surgery. The curative effect was compared between the two groups and immunological analysis was performed. Results The effective rate of observation group (92.45%) was significantly higher than that of control group (71.70%). There was no significant difference in the levels of CD3 + and CD4 + between the two groups before treatment (P> 0.05), but the levels of CD3 + and CD4 + in the observation group were higher than those in the control group (all P <0.05) ). Conclusions Laparoscopic radical gastrectomy can significantly reduce the pain of patients with advanced gastric cancer and reduce the incidence of postoperative complications. It can significantly improve the immunological indexes of CD3 + and CD4 +, and promote the early recovery of patients.