[Objective] To discuss how the content of single and double ester type alkaloids was influenced by microwave processing. [Method] Effects of hot bleaching time (A), drying temperature (B) and microwave time (C) on the content of ester type alkaloids were discussed by orthogonal design, intuitive analysis, and variance analysis. [Result] Microwave time (C) had a very significant influence on the content of double ester type alkaloids, P<0.01. Microwave time (C) had a significant influence on the content of single ester type alkaloids, P<0.05. Bleaching time (A) and drying temperature (B) only had significant influences on the content of double ester type alkaloids, P<0.05. The optimal combination of factors was A3B3C3: hot bleaching time 3 min, drying temperature 60 ℃ and microwave time 5 min. Under above conditions, the content of single and double ester type alkaloids was 802.14 and 590.33 μg/g, respectively. [Conclusion] Microwave processing could reduce the content of double ester type alkaloid, and increase the content of single ester type alkaloid. [Objective] To discuss how the content of single and double ester type alkaloids was influenced by microwave processing. [Method] Effects of hot bleaching time (A), drying temperature (B) and microwave time (C) on the content of ester type Alkaloids were discussed by orthogonal design, intuitive analysis, and variance analysis. [Result] Microwave time (C) had a very significant influence on the content of double ester type alkaloids, P <0.01. The content of single ester type alkaloids, P <0.05. Bleaching time (A) and drying temperature (B) only had significant influences on the content of double ester type alkaloids, P <0.05. The optimal combination of factors was A3B3C3: hot bleaching time 3 min, drying temperature 60 ° C and microwave time 5 min. Under the conditions, the content of single and double ester type alkaloids was 802.14 and 590.33 μg / g, respectively. [Conclusion] Microwave processing could reduce the content of double este r type alkaloid, and increase the content of single ester type alkaloid.