鼻咽癌是广东常见的恶性癌瘤之一。它与其他癌瘤一样,治疗效果与病期有密切的关系,早期患者治疗效果较好,晚期患者治疗效果往往不大理想。寻找早期发现鼻咽癌的方法是防治鼻咽癌的主要手段之一。 EB病毒特异性去氧核糖核酸酶(简称DNA酶)是一九七九年底才发现的一种酶,它能将DNA降解为去氧核糖单核苷酸,是EB病毒处于活跃状态时所产生的一种酶。一九八○年十月进一步发现了在大多数鼻咽癌患者血清中含有抗该酶的成份,便为该酶应用于鼻咽癌检测提供了可能性。 中山医学院肿瘤研究所是国内最早研究此酶的单 Nasopharyngeal cancer is one of the common malignant cancers in Guangdong. Like other cancers, the therapeutic effect has a close relationship with the disease period. Early patients have better treatment effect, and the treatment effect of advanced patients is often not ideal. The search for early detection of nasopharyngeal cancer is one of the main methods to prevent nasopharyngeal cancer. Epstein-Barr virus-specific DNase (DNase) was discovered in late 1979 as an enzyme that degrades DNA into deoxyribose mononucleotides, which are produced when EBV is active. One of the enzymes. In October 1980, it was further discovered that most patients with nasopharyngeal carcinoma had anti-enzyme components in their serum, which provided the possibility for the enzyme to be used in the detection of nasopharyngeal carcinoma. Institute of Cancer Research, Zhongshan Medical University is the earliest study of this enzyme in the country