病理性瘢痕是人类真皮内特有的纤维代谢性疾病。它发生在创伤、感染、外科手术和烧伤后，其发生机制复杂。某些细胞因子在病理性瘢痕形成过程中起重要的作用。这些因子可促使瘢痕组织中的成纤维细胞过度合成胶原蛋白等细胞外基质，从而促进细胞增殖、转化。病理性瘢痕在临床上表现为感觉异常、瘤样增生和功能障碍。 Pathological scarring is a unique metabolic disorder of the human dermis. It occurs after trauma, infection, surgery and burns, and its mechanism of occurrence is complex. Some cytokines play an important role in the pathological scar formation. These factors can promote scar tissue fibroblasts over-synthesis of collagen and other extracellular matrix, thereby promoting cell proliferation and transformation. Pathological scar in the clinical manifestations of sensory abnormalities, tumor-like proliferation and dysfunction.