在一个世纪以前甲状腺功能低下首次被描述时,它被认为是一种罕见和临床上可能致死的病种。随着后来测定血清中甲状腺激素水平技术的发展,表明甲状腺机能低下是一种常见的疾病,严重程度的范围很广。但在本世纪七十年代初以前,我们还不知道本病常见的程度如何和严重程度的范围有多广,在七十年代初促甲状腺激素(TSH)测定才 When hypothyroidism was first described a century ago, it was considered a rare and clinically lethal disease. With the subsequent determination of serum thyroid hormone levels in the development of technology, hypothyroidism is a common disease, a wide range of seriousness. However, before the early 1970s, we did not know how widespread and serious the disease was. In the early 1970s, thyroid stimulating hormone (TSH) was measured