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1975年12月1日~19日,郑州铁路司机学校暴发一起流感共161例.先后出现两次高峰,发病率29.3%.多数患者临床表现均有头痛、头晕、全身酸痛、流涕、鼻塞等典型流感症状.其中三分之一的患者有不同程度的低热及中度体温,一例高达39.7℃.采集5份患者标本全部分离出甲3型(A 3)病毒.发病第10日,二次高峰出现时,经在该校师生392人中投服复方山银胡糖衣片及金刚烷胺,发病曲线迅速下降,至服药第5日(一个疗程结束)即不再有新的病例出现.据此,初步认为两药对预防流感发病、控制暴发流行、减轻症状、缩短病程均有较好效果.现扼要报导如下:
From Dec. 1, 1975 to Dec. 19, 1975, a total of 161 outbreaks of flu were reported in the driver training school of Zhengzhou Railway. There were two peak occurrences successively, with a morbidity of 29.3%. Most patients had clinical manifestations of headache, dizziness, body aches, runny nose, stuffy nose, etc. Typical flu symptoms: One third of patients had varying degrees of fever and moderate body temperature, one case up to 39.7 ° C. Five samples of patients were collected to isolate type A (A 3) virus on the 10th day, Peak appears, by the school teachers and students in 392 people to vote compound mountain silver candy tablets and amantadine, the incidence of rapid decline in the curve, to the medication on the 5th (one course of treatment) that no new cases. Accordingly, the two drugs are preliminarily believed to be effective in preventing the onset of influenza, controlling the epidemic, alleviating the symptoms and shortening the course of disease, and the main reports are as follows: