果糖二磷酸钠是去年国家批准的二类新药,其粉针剂主要用于心血管系统疾病的治疗。果糖二磷酸钠含量的法定测定方法是二苯胺法,本注射液采用酶法。与二苯胺法相比,酶法专属性较强,准确度和精密度也符合制剂测定要求,不需要对照品,操作简便。现将酶法研究的要点介绍如下: 一、化学反应式 Fructose diphosphate was approved by the state last year, two types of new drugs, the main injection for the treatment of cardiovascular disease. Fructose diphosphate content of the legal determination of diphenylamine method, the injection of enzyme. Compared with the diphenylamine method, enzymatic specificity is strong, accuracy and precision are also in line with the requirements of the preparation determination, do not need reference substance, easy to operate. Now the key points of enzymatic research are as follows: First, the chemical reaction type