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目的观察不同类型冠心病患者同型半胱氨酸(Hcy)水平,以探讨同型半胱氨酸与冠心病发生的关系。方法检测并比较41例稳定劳力型心绞痛患者、39例不稳定型心绞痛患者、40例急性心肌梗死患者及122例健康人群Hcy水平和其他有关生化指标。结果冠心病组患者的Hcy水平、血脂、血糖、超敏C反应蛋白(hs-CRP)均明显高于健康人群,不同类型冠心病Hcy水平也有显著差异。结论高Hcy是冠心病的独立危险因素,检测Hcy可以对冠心病患者进行危险分层,还可以预测健康人群罹患冠心病的风险,及早进行干预。
Objective To observe the levels of homocysteine (Hcy) in patients with different types of coronary heart disease (CHD) to explore the relationship between homocysteine and coronary heart disease. Methods The levels of Hcy and other biochemical markers in 41 patients with stable angina pectoris, 39 patients with unstable angina pectoris, 40 patients with acute myocardial infarction and 122 healthy controls were detected and compared. Results Hcy, blood lipid, blood glucose and hs-CRP in CHD patients were significantly higher than those in healthy people, and Hcy levels in different types of CHD patients were also significantly different. Conclusions High Hcy is an independent risk factor for coronary heart disease. Hcy can be used for risk stratification in patients with coronary heart disease. It can also predict the risk of coronary heart disease in healthy people and intervene as soon as possible.