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目的:建立木鳖子中丝石竹皂苷元3-O-β-D-葡萄糖醛酸甲酯的微波提取方法,为木鳖子药材的进一步开发利用提供实验依据.方法:实验采用微波提取技术,以丝石竹皂苷元3-O-β-D-葡萄糖醛酸甲酯含量为指标,考察乙醇浓度、微波功率、提取时间及提取温度对提取工艺的影响.结果:丝石竹皂苷元3-O-β-D-葡萄糖醛酸甲酯的线性范围为0.024~0.120 mg,平均加样回收率为100.2%.微波提取的最佳提取工艺为35%乙醇65 ℃,400 w提取12 min,平均提取率为0.267%.结论:微波法提取木鳖子中丝石竹皂苷元3-O-β-D-葡萄糖醛酸甲酯的方法可靠稳定,优选出的提取工艺简单、节能、省时可行.“,”Objective: To establish the microwave extraction method of gypsogenin-3-O-glucuronide from momordica cochinchinensis, and provide the experimental basis for the further development of momordica cochinchinensis. Methods: Using microwave extraction technology, we studied the effects of ethanol concentration, microwave power, extraction time, extraction temperature on extraction process of gypsogenin-3-O-glucuronide. Results: Linear range of gypsogenin-3-O-glucuronide was 0.024~0.120 mg, and the average recovery rate was 100.2%. The best extraction process was to extract 12 minutes with 35% ethanol, 65 ℃ and 400 w. The average extraction rate was 83.4%. Conclusion: The microwave extraction method was reliable and stable to extract the gypsogenin-3-O-glucuronide from momordica cochinchinensis. At the same time, this optimized extraction process was simple, energy conversation, time-saving and feasible.