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一项最新研究发现,循环中四种生物标志物[C反应蛋白(CPR)、肿瘤坏死因子受体2(TNFR2)、同型半胱氨酸及血管内皮生长因子(VEGF)]水平增高可增加缺血性卒中事件(ISS)的发生风险;将上述标志物引入至现有评估模型中可增加卒中预测能力。研究者加拿大麦克马斯特大学的Ashkan Shoamanesh及其同事从弗明汉后代研究中入选了3224例受试者,测定其15种炎症及内皮功能障碍标志物的水平。中位随访9.3年间,共计发生缺血性卒中98例。校正年龄及性别后,循环
A recent study found that increased circulating levels of four biomarkers, including C-reactive protein (CPR), tumor necrosis factor receptor 2 (TNFR2), homocysteine, and vascular endothelial growth factor (VEGF) Risk of bloody stroke (ISS); The introduction of these markers into existing assessment models increases the ability to predict stroke. Researchers Ashkan Shoamanesh and colleagues at McMaster University in Canada selected 3224 subjects from the Framingham Offspring study to determine their levels of 15 markers of inflammation and endothelial dysfunction. During a median follow-up of 9.3 years, a total of 98 ischemic strokes occurred. After correcting for age and gender, loop