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目的探讨前列腺液(EPS)中尿酸(UA)水平与慢性前列腺炎(CP)的关系以及降低尿酸在前列腺炎治疗中意义。方法按国际慢性前列腺炎诊断标准确诊的126例CP患者为研究组,另将15例未患CP的正常人设为对照组,分别进行国际前列腺炎评分(CPSI-P),EPS中白细胞(WBC)和UA浓度测定,治疗4周后研究组再行CPSI-P、EPS中WBC、UA测定。结果①CP患者的EPS中UA水平与正常对照组差异有显著性意义(p0.05)。②慢性前列腺炎患者治疗前后CPSI-P,EPS中UA对比有显著性差异(p0.05),而EPS中WBC在治疗前后差异无显著性意义(p>0.05)。结论EPS中UA水平可能与CP发病有关,EPS中UA测定可能是CP诊断及其疗效监测的有用指标之一。
Objective To investigate the relationship between uric acid (UA) in prostatic fluid (EPS) and chronic prostatitis (CP) and to reduce the significance of uric acid in the treatment of prostatitis. Methods According to the diagnostic criteria of international chronic prostatitis, 126 patients with CP were selected as the study group. Another 15 healthy individuals without CP were enrolled as the control group. The international prostatitis score (CPSI-P), white blood cell (WBC) ) And UA concentration. After 4 weeks of treatment, CPSI-P, WBC and UA in EPS were determined in the study group. Results ① The level of UA in EPS of CP patients was significantly different from that of the control group (p <0.05). ② There was significant difference in UA between CPSI-P and EPS before and after treatment of chronic prostatitis (p <0.05), but there was no significant difference in EPS between WBC before and after treatment (p> 0.05). Conclusion The UA level in EPS may be related to the pathogenesis of CP, and UA in EPS may be one of the useful indicators for the diagnosis of CP and its efficacy.