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目的探讨药剂科协同医院的行政干预对促进抗菌药物合理应用的作用。方法回顾性分析药剂科对促进抗菌药物合理应用在协同行政干预前后抗菌药物指标完成的变化。结果协同行政干预后与未干预前变化:住院患者抗菌药物使用率分别由73.2%降至53.4%,门诊抗菌药物使用率由40.0%降至为12.8%,抗菌药物使用强度由67.8DDD降至36.8DDD,标本送检率由24.0%上升到51.0%,Ⅰ类切口手术预防使用抗菌药物比例由61.1%降至29.0%,预防用药时间不超时限比例由36.0%上升至86.0%,术前预防用药时机正确率由47.0%上升到71.0%。结论药剂科协同医院行政干预后可明显提高抗菌药物的临床合理应用。
Objective To explore the role of administrative intervention in pharmacy collaborative hospital to promote rational use of antimicrobial agents. Methods Retrospective analysis of pharmacy department to promote the rational use of antimicrobial agents before and after the administration of antimicrobial interventions to complete the changes in indicators. Results The changes of synergistic administrative intervention before and after intervention: the inpatients’ antimicrobial use rate decreased from 73.2% to 53.4% respectively, the outpatient antimicrobial use rate decreased from 40.0% to 12.8%, and the antimicrobial use intensity decreased from 67.8DDD to 36.8 DDD, the rate of specimen submission increased from 24.0% to 51.0%. The proportion of anti-bacterial drugs used in prevention of type Ⅰ incision decreased from 61.1% to 29.0%, and the proportion of time to prevent from overdue increased from 36.0% to 86.0%. Preoperative prophylaxis The timing accuracy increased from 47.0% to 71.0%. Conclusion Pharmacology collaborative hospital administrative intervention can significantly improve the clinical rational use of antimicrobial agents.