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目的:观察速溶芦笋粉对小鼠睡眠的改善作用。方法:18～22 g健康雄性昆明种小鼠,随机分为5组,每组10只,皂苷含量为15%速溶芦笋粉低、中、高剂量组(85,170,510 mg·kg-1)、空白对照组、阳性对照组(酸枣仁皂苷360 mg·kg-1),连续ig 30 d后,进行戊巴比妥钠阈下剂量催眠试验、戊巴比妥钠睡眠潜伏期试验、延长戊巴比妥钠睡眠时间试验,观察对小鼠睡眠的影响。结果:速溶芦笋粉具有协同戊巴比妥钠阈下剂量催眠作用、可显著缩短戊巴比妥钠睡眠潜伏期、显著延长戊巴比妥钠睡眠时间。结论:速溶芦笋粉具有改善睡眠的作用。
Objective: To observe the effect of instant asparagus powder on improving sleep in mice. Methods: Healthy male Kunming mice (18-22 g) were randomly divided into five groups with 10 mice in each group. The content of saponin was 15%, the low, medium and high dose of asparagus powder (85,170 and 510 mg · kg -1) Group and the positive control group (Jujuboside 360 mg · kg-1) for 30 d, the subliminal hypnotic test of pentobarbital sodium, the sleep latency test of pentobarbital sodium, the prolonged sodium pentobarbital Sleep time test to observe the impact of sleep on mice. Results: Instant asparagus powder synergized with subthreshold pentobarbital dose hypnotic effect, can significantly shorten the latency of pentobarbital sodium sleep significantly prolonged sodium pentobarbital sleep time. Conclusion: Instant asparagus powder has the effect of improving sleep.