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目的:观察7日、10日疗程的三联疗法根除Hp的疗效。方法:将76例Hp阳性的胃炎、消化性溃疡患者随机分为7日疗法和10日疗法两组,均采用奥美拉唑、阿莫西林、克拉霉素,每日服药2次,疗程结束后观察Hp根除情况以及药物不良反应。结果:10日疗程Hp根除率显著高于7日疗程,差异有统计学意义(P<0.05),,且药物不良反应发生率小。结论:10日疗程Hp根除率较为满意,且药物不良反应无明显增加。
Objective: To observe the efficacy of triple therapy for eradicating Hp on the 7th and 10th days. Methods: 76 Hp-positive gastritis and peptic ulcer patients were randomly divided into 7-day treatment and 10-day treatment. All patients were treated with omeprazole, amoxicillin and clarithromycin twice daily. The course of treatment was over After the observation of Hp eradication and adverse drug reactions. Results: The Hp eradication rate on the 10th was significantly higher than that on the 7th, with a significant difference (P <0.05), and the incidence of adverse drug reactions was small. Conclusion: The Hp eradication rate was satisfactory on the 10th and the adverse drug reaction did not increase significantly.