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目的对急性脑梗死和高敏C反应蛋白(hs-CRP)水平及颈动脉斑块的性质关系进行探讨。方法 72例急性脑梗死患者(观察组)与58例健康体检者(对照组)作为研究对象,检测两组的高敏C反应蛋白水平,对其和颈动脉斑块性质关系进行探讨。结果观察组的hs-CRP水平、斑块检出率均明显高于对照组(P<0.05);急性脑梗死不稳定斑块患者与稳定斑块、无斑块患者的hs-CRP水平对比,差异有统计学意义(P<0.05);稳定斑块患者与无斑块患者的hs-CRP水平对比,差异无统计学意义(P>0.05)。结论急性脑梗死患者和高敏C反应蛋白水平、颈动脉斑块性质具有密切关系,可将其作为对急性脑梗死程度进行判断的重要指标,能够对急性脑梗死疾病的诊断、治疗提供重要依据。
Objective To investigate the relationship between acute cerebral infarction, high-sensitivity C-reactive protein (hs-CRP) and carotid plaque. Methods Seventy-two patients with acute cerebral infarction (observation group) and 58 healthy subjects (control group) were selected as study objects. The levels of high-sensitivity C-reactive protein in both groups were detected and their relationship with carotid plaque properties was discussed. Results The hs-CRP level and plaque detection rate in the observation group were significantly higher than those in the control group (P <0.05). The hs-CRP levels in patients with unstable plaque in acute cerebral infarction were significantly higher than those in stable plaque and plaque- (P <0.05). There was no significant difference in hs-CRP levels between patients with stable plaque and those without plaque (P> 0.05). Conclusions Patients with acute cerebral infarction and high-sensitivity C-reactive protein levels, carotid plaque properties are closely related, which can be used as an important indicator of the degree of acute cerebral infarction can provide an important basis for the diagnosis and treatment of acute cerebral infarction disease.