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２６例骨髓增生异常综合征（ＭＤＳ）外周血淋巴、单核细胞在不同状态时生成白细胞介素６（ＩＬ－６）水平用生物法检测，发现：患者淋巴细胞在无丝裂原刺激时生成ＩＬ－６与正常人无差异（Ｐ＞０．０５），刺激后ＲＡＥＢ及ＲＡＥＢ－ｔ者低于正常（Ｐ＜０．０５，Ｐ＜０．０１）；患者单核细胞在无刺激状态下生成水平高于正常人（Ｐ＜０．０５或Ｐ＜０．０１），刺激后ＲＡＥＢ及ＲＡＥＢ－ｔ者则低于正常人（Ｐ＜０．０１）。认为：患者单核细胞自产生ＩＬ－６增高；ＲＡＥＢ及ＲＡＥＢ－ｔ的淋巴、单核细胞对丝裂原反应性降低。
26 cases of myelodysplastic syndrome (MDS) peripheral blood lymphocytes, mononuclear cells in different states to generate interleukin 6 (IL-6) levels detected by biological method, found that: patients with lymphocytes in the absence of mitogen stimulation generated The levels of IL-6 in RAEB and RAEB-t were lower than those in normal controls (P <0.05, P <0.01). The number of monocytes in non-stimulated (P <0.05 or P <0.01). The levels of RAEB and RAEB-t were lower than those of normal controls (P <0.01). It is considered that monocytes from patients produce elevated IL-6, and lymphoid and mononuclear cells from RAEB and RAEB-t are less responsive to mitogen.