作者复习了抗抑郁药引起皮肤副反应的有关文献。皮疹的患病率约在2%到4%之间,用某些药后患病率更高,如麦普替林和卡马西平。抗抑郁剂可导致各种皮肤形态结构的改变,但以出疹性皮疹为主。不论其发病是否以免疫机制为中介,皮肤反应的类型均相似。文章讨论了对用药后出现皮肤副反应的处理,并提出了许多建议。 The authors reviewed antidepressants caused by skin side effects of the literature. The prevalence of rashes is between 2% and 4%, with a higher prevalence of certain drugs, such as topotecan and carbamazepine. Antidepressants can cause a variety of skin morphological changes, but mainly rash rash. Regardless of whether the disease is mediated by the immune mechanism, the types of skin reactions are similar. The article discusses the treatment of skin side effects after treatment, and made many recommendations.