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目的对瑞舒伐他汀(可定)在不同强化时间里对高龄冠心病患者降血脂临床疗效进行观察。方法对100例年龄在72岁～85岁的高龄冠心病患者每天给予20mg的瑞舒伐他汀进行治疗,并检测患者治疗前以及治疗后2周、4周血脂的变化水平,记录患者在进行治疗过程中发生的变化。结果患者进行治疗2周后检测可知,患者的血脂水平与治疗前进行对比,血脂中的TC、TG、LDL-C,均差异有统计学意义(P<0.05)。治疗4周后患者的TC、TG、LDL-C水平与治疗前进行对比,均出现显著性的差异(P<0.05),其中HDL-C的升高,差异存在显著性(P<0.05).结论对高龄冠心病患者采用瑞舒伐他汀进行治疗,每天用量为20mg,可有效地降低TC、TG以及LDL-C的水平,患者中没有出现不良的反应。
Objective To observe the clinical effect of rosuvastatin (fixed) on lowering blood lipid in elderly patients with coronary heart disease in different intensified time. Methods A total of 100 elderly coronary heart disease patients aged 72-85 years were given 20 mg of rosuvastatin daily for treatment. The levels of lipids in the patients before and after 2 and 4 weeks of treatment were measured, and the patients were treated Changes that have taken place in the process. Results After 2 weeks of treatment, the levels of TC, TG and LDL-C in blood lipids were significantly different between the two groups (P <0.05). The levels of TC, TG and LDL-C in patients after treatment for 4 weeks were significantly different from those before treatment (P <0.05). There was a significant difference in HDL-C between the two groups (P <0.05). Conclusion Rosuvastatin is administered to elderly patients with coronary heart disease. The daily dosage of 20 mg can effectively reduce the levels of TC, TG and LDL-C, and no adverse reaction occurs in patients.