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为观察尼卡地平伍用小剂量芬太尼预防老年患者气管插管时心血管反应的效果和优点，选择择期腹部手术３０例年龄＞６０岁的患者随机分成２组，每组１５例，全麻诱导采用静脉注射芬太尼、依托脒酯、琥珀胆碱，Ⅰ组插管前１ｍｉｎ静注尼卡地平０．０２ｍｇ／ｋｇ，Ⅱ组插管前１ｍｉｎ静注４ｍｌ生理盐水。监测并记录诱导前、插管即刻、插管后１ｍｉｎ、３ｍｉｎ、５ｍｉｎ的血流动力学参数。结果：对照组各项指标均显著升高（Ｐ＜０．０５），而尼卡地平组较为平稳。表明静注尼卡地平和芬太尼可有效地抑制老年患气管插管时的心血管反应。
In order to observe the effect and advantages of nicardipine combined with low-dose fentanyl in preventing cardiovascular reactions in elderly patients during tracheal intubation, 30 patients aged> 60 years who underwent elective abdominal surgery were randomly divided into two groups of 15 patients Induction of anesthesia with intravenous injection of fentanyl, relying on amidine ester, succinylcholine, Ⅰ group 1min before intubation nicardipine 0.02mg / kg intravenous infusion of 1ml group before intubation 4ml saline. The hemodynamic parameters of pre-induction, immediate intubation, 1 min, 3 min, 5 min after intubation were monitored and recorded. Results: All the indexes of the control group were significantly increased (P <0.05), while the nicardipine group was relatively stable. This suggests that intravenous nicardipine and fentanyl can effectively suppress cardiovascular reactions in elderly patients with endotracheal intubation.