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目的:分析兰州市甲状腺疾病患者构成及临床特征，为甲状腺疾病的预防和治疗提供经验和依据。方法:收集和整理2008年10月至2018年10月兰州军区总医院安宁分院收治的甲状腺疾病患者病历资料，分析年龄、性别、职业、甲状腺疾病分型及甲状腺激素水平等情况。结果:共收集375例甲状腺疾病住院患者病历资料，其中男性114人、女性261人，分别占30.4%和69.6%。甲状腺结节、甲状腺功能减退、甲状腺功能亢进、单纯性甲状腺肿、甲状腺炎、甲状腺腺瘤和甲状腺癌分别占12.3%（46/375）、22.9%（86/375）、10.4%（39/375）、7.5%（28/375）、5.9%（22/375）、40.0%（150/375）和1.1%（4/375）。不同性别间甲状腺功能减退和甲状腺腺瘤构成情况比较差异有统计学意义（n P均< 0.05）；不同年龄段甲状腺功能减退、甲状腺功能亢进和甲状腺腺瘤构成情况比较差异有统计学意义（n P均< 0.05）；不同职业间甲状腺功能减退和甲状腺腺瘤构成情况比较差异有统计学意义（n P均< 0.05）。甲状腺功能亢进患者血清促甲状腺素（TSH）、游离三碘甲状腺原氨酸（FTn 3）和游离甲状腺素（FTn 4）诊断符合率分别为43.6%（17/39）、79.5%（31/39）和89.7%（35/39），甲状腺功能减退患者TSH、FTn 4和FTn 3诊断符合率分别为60.5%（52/86）、44.2%（38/86）和2.3%（2/86），甲状腺结节、甲状腺炎、单纯性甲状腺肿和甲状腺腺瘤患者以FTn 3升高和三碘甲状腺原氨酸（Tn 3）降低为主。n 结论:兰州市甲状腺疾病以甲状腺腺瘤和甲状腺功能减退为主；女性和年龄≥50岁人群高发，甲状腺功能亢进有低龄化倾向，应加大甲状腺疾病的体检和筛查。“,”Objective:To analyze the constitution and clinical characteristics of patients with thyroid diseases in Lanzhou, and to provide experience and basis for clinical treatment and prevention of thyroid diseases.Methods:The data of inpatients with thyroid diseases of Anning Branch of General Hospital of Lanzhou Military Region from October 2008 to October 2018 were collected, and the differences of age, gender, occupation, thyroid disease classification and composition, and thyroid hormone levels were analyzed.Results:A total of 375 inpatients data with thyroid diseases were collected, including 114 males and 261 females, accounting for 30.4% and 69.6%, respectively. Thyroid nodules, hypothyroidism, hyperthyroidism, goiter, thyroiditis, thyroid adenoma and thyroid cancer accounted for 12.3% (46/375), 22.9% (86/375), 10.4% (39/375), 7.5% (28/375), 5.9% (22/375), 40.0% (150/375) and 1.1% (4/375), respectively. There were significant differences in hypothyroidism and thyroid adenoma between different genders (n P < 0.05). There were significant differences in hypothyroidism, hyperthyroidism and thyroid adenoma between different age groups( n P < 0.05). There were significant differences in hypothyroidism and thyroid adenoma between different occupations ( n P < 0.05). The diagnostic coincidence rates of thyroid stimulating hormone (TSH), free triiodothyroine (FT n 3) and free thyroine (FTn 4) of inpatients with hyperthyroidism were 43.6% (17/39), 79.5% (31/39) and 89.7% (35/39), respectively. The diagnostic coincidence rates of TSH, FTn 4 and FTn 3 of inpatients with hypothyroidism were 60.5% (52/86), 44.2% (38/86) and 2.3% (2/86), respectively. The patients with thyroid nodules, thyroiditis, goiter and thyroid adenoma mainly had elevated FTn 3 and decreased Tn 3 levels.n Conclusions:Thyroid adenoma and hypothyroidism are the main thyroid diseases in Lanzhou. The incidence in women and aged ≥50 years old people is high, and hyperthyroidism tends to be younger. Therefore, it is necessary to strengthen the physical examination and screening of thyroid diseases.