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我院从住院下呼吸道感染患者痰定量培养分离出绿脓杆菌菌落数≥１０１０／Ｌ，及时急重症采用间接荧光抗体染色法阳性者确定为绿脓杆菌下呼吸道感染９３例。其中８０株细菌中β－内酰胺酶阳性率占３３．７％（２７／８０），血清学分型以Ｇ型和Ｉ型为多。８种抗生素对９３株绿脓杆菌耐药，以ＰＩＰＣ最高占３１．２％（２９／９３），ＡＺＴ、ＣＦＳ最低各占５．４％（５／９３）．绿脓杆菌感染后病情更复杂，故病死率高，虽积极治疗，但病死率仍为１６．１％。抗生素治疗不当会诱导耐药使病情更复杂，恰当治疗非常重要。
In our hospital from the hospitalized patients with respiratory tract infection sputum quantitative culture isolated Pseudomonas aeruginosa colonies count ≥1010 / L, acute and severe disease by indirect fluorescent antibody staining was confirmed as Pseudomonas aeruginosa lower respiratory tract infection in 93 cases. Among them, the positive rate of β-lactamase in 80 strains of bacteria was 33.7% (27/80), serotypes were mostly G-type and I-type. Eight kinds of antibiotics were resistant to 93 strains of Pseudomonas aeruginosa. The highest PIPC was 31.2% (29/93), and the lowest was AZT and CFS (5.4%, 5/93) respectively. Pseudomonas aeruginosa infection more complicated, so the case fatality rate, although aggressive treatment, but the mortality rate is still 16.1%. Improper treatment of antibiotics will induce resistance to make the condition more complex and proper treatment is very important.