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目的:研究环境亮度及瞳孔直径对神经对比敏感度函数(NCSF)的影响,并与对比敏感度函数(CSF)相比较。方法:招募健康男性志愿者10名10眼作为受试者,以右眼为测试眼,利用视觉监视系统设置不同环境亮度并附加眩光,测量自然、3.0mm和5.0mm瞳孔时的CSF;利用视觉质量分析仪测量3.0mm和5.0mm瞳孔时的调制传递函数(MTF),根据CSF与MTF的比值求得NCSF。结果:NCSF和CSF随环境亮度降低曲线整体下移,波峰向低频区移动,CSF更偏向低频区。CSF变化受NCSF和MTF共同作用,瞳孔开大,MTF下降,在明视觉环境和中间视觉环境中,NCSF和CSF上升,主要上升区为中低频区;当亮度较高或存在眩光源时,NCSF和CSF在中低频区上升不明显,在高频区有下降的趋势;在暗视觉环境中,小范围的瞳孔波动对NCSF和CSF没有显著影响。结论:NCSF能够反映视觉神经系统的功能,与MTF共同决定CSF。CSF曲线形状与NCSF相近,波峰更偏向低频区。环境亮度降低会使NCSF下降,CSF随之下降;瞳孔开大会使NCSF在中低频区上升,CSF随之上升,而环境较亮或存在眩光源时,NCSF和CSF在高频区都有下降的趋势。
OBJECTIVE: To study the effect of ambient brightness and pupil diameter on neural contrast sensitivity function (NCSF) and to compare with contrast sensitivity function (CSF). Methods: 10 healthy volunteers were enrolled in this study. 10 eyes of healthy male volunteers were enrolled in this study. The right eye was used as the test eye, and the visual monitoring system was used to set different ambient brightness and add glare to measure natural, 3.0mm and 5.0mm pupils. The mass analyzer measures the modulation transfer function (MTF) at 3.0 mm and 5.0 mm pupils, and the NCSF is calculated from the ratio of CSF to MTF. Results: The curve of NCSF and CSF decreased with the decrease of ambient brightness, the peak moved to the low frequency region, and the CSF was more inclined to the low frequency region. CSF changes are affected by the combination of NCSF and MTF, pupil opening large, MTF decreased in the visual environment and the middle visual environment, NCSF and CSF increased, the main rising area for the low frequency region; when the brightness is high or glare source, NCSF And CSF did not increase significantly in the middle and low frequency regions, but decreased in the high frequency regions. In the dark visual environment, small-sized pupil fluctuations had no significant effect on NCSF and CSF. Conclusion: NCSF can reflect the function of the visual nervous system and determine CSF together with MTF. The shape of CSF curve is similar to that of NCSF, and the peaks are more inclined to the low frequency region. The decrease of ambient brightness led to the decline of NCSF and the drop of CSF. The opening of NCSF increased the CSF of the NCSF in the middle and low frequency regions, while the CSF of the NCSF increased in the light of the bright environment or the glare source. trend.