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本文以恶性疟原虫配子体血症病人血，喂词大劣按蚊，血餐后11～13d，解剖唾液腺，计数子孢子感染率。本芴醇服药前及药后24、48h腺感染率分别为35．0、9．1、3．8％（P＜0．05）；本芴醇分别与蒿甲醚、双氢青蒿素、青蒿琥酯伍用，治疗前腺感染率分别为25．4、42．6、63．2％，服药后48h皆降至0：蒿甲醚、双氢青蒿素、有篙琥酯单独使用，治前腺感染率分别为14．3、67．9、5．3％，治后48h分别为5.4、26．8、4．3％。表明本芴醇有一定的抑制孢子增殖效果，它与青蒿素衍生物分别配伍应用，能明显提高抑制孢子增殖的作用。
In this paper, Plasmodium falciparum gametoma patients with blood, fed anopheles anopheles, 11 ~ 13d after blood meal dissection of salivary glands, count the rate of infection of sporozoites. The bacterial infection rates of benflumetol before and 24 and 48 hours after treatment were 35.0, 9.1 and 3.8%, respectively (P <0.05). The relative bioavailability of benflumetol to artemether, dihydroartemisinin , Artesunate with Wu, before treatment, gland infection rates were 25.4,42.6,63.2%, 48h after treatment were reduced to 0: artemether, dihydroartemisinin, Used alone, preadmission gland infection rates were 14.3,67.9,5.3%, 48h after treatment were 5.4,26.8,4.3%. Show that lumefantrine has a certain inhibitory effect on spore proliferation, and artemisinin derivatives were used in combination, can significantly improve the inhibition of spore proliferation.