论文部分内容阅读
目的探讨螺内酯对扩张型心肌病心力衰竭的治疗作用。方法将119例患者按入选顺序随机分编入治疗组和对照组。对照组接受常规治疗(β受体阻滞剂+ACEI+地高辛+速尿),治疗组在对照组的基础上加安体舒通(螺内酯()20mg BID)。结果治疗1a后,左房、左室内经明显小于对照组,左室射血分数,左室短轴缩短率明显高于对照组。结论螺内酯对扩张型心肌病心力衰竭有效,可改善心功能和改善心室重构,改善预后。
Objective To investigate the therapeutic effect of spironolactone on heart failure of dilated cardiomyopathy. Methods 119 patients were randomly divided into treatment group and control group according to the order of selection. The control group received routine treatment (β blockers + ACEI + digoxin + furosemide). The treatment group was given diazepam (20 mg BID) on the basis of the control group. Results After treatment 1a, left atrium and left ventricle were significantly smaller than the control group, left ventricular ejection fraction, left ventricular short axis shortening rate was significantly higher than the control group. Conclusion Spironolactone is effective in heart failure of dilated cardiomyopathy and can improve cardiac function, improve ventricular remodeling and improve prognosis.