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目的探讨2型糖尿病(T2DM)合并非酒精性脂肪肝(NAFLD)的危险因素。方法 T2DM合并脂肪肝组294例(A组)与无脂肪肝组297例(B组),进行临床相关因素对比分析和维、汉对比分析。Logistic回归进行危险因素分析。结果 A组BMI、WL、TG及HOMAIR明显增高(P<0.01);LDL、HABIC、ALT增高(P<0.05);维族BMI、WL、TG、HOMA-IR较汉族明显增加(P<0.01),A组中维族HBAIC增高(P<0.05);WL、TG、HOMA-IR是NAFLD的危险因素(OR值分别为1.104、2.473、2.323)。结论 T2DM合并NAFLD存在明显的肥胖、血脂紊乱及IR,维吾尔族糖尿病患者更明显。WL、TG、HOMA-IR是NAFLD的主要危险因素。
Objective To investigate the risk factors of type 2 diabetes mellitus (T2DM) complicated with non-alcoholic fatty liver disease (NAFLD). Methods A total of 294 patients with T2DM complicated with fatty liver (group A) and 297 patients without fatty liver (group B) were included in the study. Logistic regression analysis of risk factors. Results The levels of BMI, WL, TG and HOMA-IR in group A were significantly increased (P <0.01), the levels of LDL, HABIC and ALT in group A were significantly higher than those in Han (P <0.01) The level of HBAIC in Uighur group was higher in group A (P <0.05). WL, TG and HOMA-IR were risk factors of NAFLD (OR = 1.104, 2.473 and 2.323, respectively). Conclusions There is obvious obesity, dyslipidemia and IR in diabetic T2DM with NAFLD and more obvious in Uygur diabetic patients. WL, TG, HOMA-IR are the main risk factors for NAFLD.