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过氧化氢是组织的高毒性的代谢产物,而过氧化氢酶是过氧化氢代谢中一种重要的酶。据报告大鼠子宫内铜丝可激活宫内膜过氧化氢酶,作者研究了置IUD对宫内膜中过氧化氢生成率的影响。内膜标本取自:①未采用节育方法的10名健康育龄(20~40岁)妇女(正常组);②置CuT或Lippes100P 6个月至5年3个月的20名25~45岁
Hydrogen peroxide is a highly toxic metabolite of tissues, and catalase is an important enzyme in hydrogen peroxide metabolism. The intrauterine copper catalase has been reported to activate endomembrane catalase in rats, and the authors studied the effect of IUD on the rate of hydrogen peroxide production in the endometrium. Endometrial specimens were collected from: ① 10 healthy women of reproductive age (20 ~ 40 years) who did not use birth control method (normal group); ② 20 patients 25 ~ 45 years old with CuT or Lippes100P 6 months to 5 years and 3 months