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作者复查了１９８５～１９８８年间美国马里兰大学牙科学院口腔病理系活检材料，观察了口腔巨细胞性纤维瘤和刺激性纤维瘤。结果发现，二者分别占同期活检标本的１．８％和７．４％，发病年龄有明显的规律性。发病部位前者以牙龈受累最多见，后者以颊部最多见，病理改变：前者以病变中出现细胞体较大的梭形细胞及星状细胞为病理学诊断依据，时常可见双核或多核巨细胞。刺激性纤维瘤中富有胶原纤维和成熟纤维细胞，小血管周围见有少量慢性炎性细胞浸润。
The authors reviewed the biopsy materials from Department of Oral Pathology, University of Maryland, College of Dentistry from 1985 to 1988 and observed oral giant cell fibroma and irritating fibroids. The results showed that the two accounted for 1.8% and 7.4% of the same biopsy specimens, the age of onset have obvious regularity. The incidence of the former part of the gums to see the most common, the latter to see the most buccal, pathological changes: the former lesions occur in large cell bodies spindle cells and stellate cells for pathological diagnosis based on the often visible dual-core or multinucleated giant cells . Irritable fibroids are rich in collagen fibers and mature fibroblasts, small blood vessels see a small amount of chronic inflammatory cell infiltration.