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目的探讨血液流变学在评价大容量全肺灌洗（ＷＬＬ）治疗矽肺疗效中的应用。方法对３０例实施ＷＬＬ治疗的矽肺患者作了灌洗前后血液流变学的动态观察及肺功能测定、血气分析。结果ＷＬＬ治疗的矽肺患者由于肺通气功能的改善及动脉血氧分压（ＰａＯ２）的提高，其高粘滞血症、红细胞聚集、红细胞变形异常、Ｃａｓｏｎ屈服应力增高状态有明显改善，各项指标均趋于正常。结论血液流变学检查在评价ＷＬＬ治疗矽肺的疗效中具有重要作用
Objective To investigate the application of hemorheology in the evaluation of the therapeutic effect of high volume whole lung lavage (WLL) on silicosis. Methods Thirty patients with silicosis who underwent WLL treatment were studied on hemorheology and pulmonary function before and after lavage. Blood gas analysis was performed. Results The WLL-treated patients with silicosis had significantly improved hyperviscosity, erythrocyte aggregation, abnormal erythrocytes and increased Cason yield stress due to the improvement of pulmonary ventilation and the increase of arterial oxygen tension (PaO2) All tend to be normal. Conclusion Hemorheological examination plays an important role in evaluating the efficacy of WLL in the treatment of silicosis