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目的分析手术治疗原发性食管小细胞癌的疗效。方法选择我院2004年8月至2006年6月26例行手术治疗的食管小细胞癌患者,所有患者均随访1～5年,对手术治疗后的效果,患者1、3、5年生存率进行观察。结果 26例食管小细胞癌患者后术后TNM分期Ⅰ期1、3、5年生存率分别为100%(6/6),66.67%(4/6),33.33%(2/6)。TNM分期Ⅱ期1、3、5年生存率分别为42.86%(6/14),7.14%(1/14),0(0/14)。TNM分期Ⅲ期生存率分别为33.33%(2/6),0(0/14),0(0/14)。患者死亡原因均为肿瘤转移至肝、肺等部位。结论原发性食管小细胞癌预后极差,外科手术是治疗I、Ⅱ期病例的主要治疗手段,术后化疗可提高疗效;对于Ⅲ、Ⅳ期病例,则应以化疗和放疗为主要治疗手段。
Objective To analyze the curative effect of surgical treatment of primary esophageal small cell carcinoma. Methods A total of 26 patients with esophageal small cell carcinoma underwent surgical treatment from August 2004 to June 2006 in our hospital. All patients were followed up for 1 to 5 years. The effect on the postoperative treatment, the 1, 3, 5 year survival rate Observe. Results The survival rates of 1, 3, 5 year after TNM staging in 26 patients with esophageal small cell carcinoma were 100% (6/6), 66.67% (4/6) and 33.33% (2/6), respectively. The 1, 3, 5-year survival rates of TNM stage Ⅱ were 42.86% (6/14), 7.14% (1/14) and 0 (0/14) respectively. The TNM stage Ⅲ survival rates were 33.33% (2/6), 0 (0/14) and 0 (0/14), respectively. The causes of death of patients were tumor metastasis to the liver, lungs and other parts. Conclusions Primary esophageal small cell carcinoma has very poor prognosis. Surgery is the main treatment for stage I and II patients. Postoperative chemotherapy can improve the curative effect. For stage III and IV cases, chemotherapy and radiotherapy should be the main treatment .