神经纤维瘤恶性变已众所周知,特别是见于多发性神经纤维瘤病,约3%的病例可发生恶性变.半数以上的恶性神经纤维肉瘤合并有多发性神经纤维瘤病,但椎管内恶性神经纤维瘤则罕见,尚未见文献报导.本文报导一例男性42岁患者,主诉下腰痛9年,进行性双下肢力弱3周,入院前一天发展为不全截瘫.入院后经各项检查,包括脊髓造影确定为T_(12)～S_1椎管内肿瘤,行T_(12)～L_4椎板切除手术探查,发现硬脊膜内有一灰蓝色、柔软、血管 The malignant transformation of neurofibromatosis is well known, especially seen in patients with multiple neurofibromatosis, malignant transformation can occur in about 3% of cases. More than half of malignant neurofibrosarcoma with multiple neurofibromatosis, but the spinal nerves Fibroids are rare and have not been reported in the literature. This article reports a case of a 42-year-old male patient who complained of low back pain for 9 years. She had weak double-limb weakness for 3 weeks. He developed paraplegia on the day before admission. After examination, including spinal cord The angiography was identified as T_(12)~S_1 intraspinal tumors. T_(12)~L_4 laminectomy was performed to find out that there was a gray blue, soft, blood vessels in the dura.