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白塞病(BD)是一种病因不明的慢性、反复发作性、多系统受累的血管炎性疾病，常见临床表现为复发性口腔和生殖器溃疡、葡萄膜炎和皮肤损害等。BD累及神经系统则称为神经白塞病(NBD)，可表现为脑或脊髓实质损害、脑静脉血栓形成、脑动脉炎等。本文主要围绕NBD的临床表现、辅助检查、诊治等方面的研究进展进行综述，以期为NBD的临床诊疗提供参考。“,”Beh?et's disease (BD) is a chronic, relapsed, and inflammatory vascular disease, usually with multiple systems involvement. Recurrent oral and genital ulcers, uveitis and skin lesions are common clinical manifestations. When nervous system gets involved, it is called Neuro-Beh?et's disease (NBD). NBD can lead to parenchymal damage to the brain or spinal cord, cerebral venous thrombosis and arterial vasculitis. Our review focuses on the clinical manifestations, auxiliary examination, diagnosis and treatment of NBD.