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呼吸衰竭的药物治疗包括以下几个方面: 一、控制感染: 呼吸道感染是诱发和加重呼吸衰竭的重要因素,常是促进呼衰的死亡原因之一,因此控制感染是治疗呼衰的关键。呼吸道的病原体绝大多数为细菌类,所以,抗生素是治疗呼衰的重要药物。 (一)抗生素用药原则: 1、针对性:选择对感染菌种针对性强的抗生素,在短期内杀灭和抑制细菌生长以控制感染。 2、足量:由于抗生素应用几十年,很多细菌对抗生素产生了抗药性,另外,要使抗生素通过血一肺屏障或血一支气管屏障达到肺泡及支气管的有效抗菌浓度,均必须增加抗生素的剂量。 3、联合:呼衰时往往是多种细菌混合感染,
Respiratory failure drug treatment includes the following aspects: First, the control of infection: respiratory tract infection is induced and aggravated respiratory failure, an important factor, often to promote respiratory failure, one of the causes of death, so control of infection is the key to the treatment of respiratory failure. Respiratory pathogens most of the bacteria, therefore, antibiotics is an important drug for the treatment of respiratory failure. (A) the principle of antibiotic medication: 1, targeted: Select the antibiotics targeted against infected bacteria in the short term to kill and inhibit bacterial growth to control infection. 2, enough: due to antibiotic applications for decades, many bacteria have antibiotic resistance, in addition, to make antibiotics through the blood a lung barrier or blood a bronchial barrier to reach the effective antibacterial alveolar and bronchial concentrations, must increase the antibiotic dose. 3, joint: respiratory failure is often a mixture of multiple bacteria infection,