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目的:研究并分析临床在男性不育患者的治疗过程中,评价应用芳香化酶抑制剂的临床效果,为临床的不育治疗奠定基础。方法:在我院相关科室选择了2014年5月到2015年5月期间收治的男性不育患者,随机抽取78例作为研究对象,分别采用两种不同的治疗方案并评价其疗效。结果:经芳香化酶抑制剂治疗的试验组的各项指标(精子活力、TH/TP)显著优于对照组,差异显著(P<0.05)。对比两组患者配偶的妊娠率发现,经芳香化酶抑制剂治疗的试验组妊娠率(9/39,23.08%)显著高于对照组(4/39,10.26%),差异显著(P<0.05)。结论:在男性不育患者的治疗过程中,应用芳香化酶抑制剂可提升精子活动率及密度,进而使患者的精液质量得到大幅度的改善,为临床的不育治疗奠定基础,应广泛推广。
Objective: To study and analyze the clinical application of aromatase inhibitors in the treatment of male infertility, and to lay the foundation for clinical infertility treatment. Methods: A total of 78 infertile male patients who were admitted to our department from May 2014 to May 2015 were selected randomly. Two different treatment regimens were used to evaluate their efficacy. Results: The indexes (sperm motility, TH / TP) of the experimental group treated with aromatase inhibitor were significantly better than those of the control group (P <0.05). Comparing the pregnancy rates of spouses in two groups, the pregnancy rate (9/39, 23.08%) in the experimental group treated with aromatase inhibitor was significantly higher than that in the control group (4/39 and 10.26%) (P <0.05 ). Conclusion: The application of aromatase inhibitors can increase sperm motility and density in the treatment of male infertility patients, which in turn can greatly improve the quality of patients’ semen, which lays the foundation for clinical infertility treatment and should be widely promoted .