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应用电感耦合等离子体-原子发射光谱法(ICP-AES)和原子荧光光谱法(AFS)对广西12个不同产地两面针根的19种微量元素进行分析测定,该方法通过硝酸-高氯酸消解体系,有效彻底地消解样品中的有机物;而对于易挥发元素汞、硒,则通过控制样品的消解量、消解温度和消解时间,从而达到最佳的消解效果。该方法简单、高效、试剂用量少、结果准确,加标回收率为90.12%—104.14%,精密度均小于3%。结果表明,不同产地中药两面针根的微量元素含量有异,Na、Mg、K、Ca、Zn、Mn几种人体必需微量元素在不同产地两面针根的含量丰富,重金属元素Cr、As未检出,12个产地的Hg和11个产地的Pb均符合药用和出口标准,但Cd含量均超过药用和出口标准。此结果为研究两面针药材微量元素和药效相关性提供有效的数据,为两面针规范化种植基地选择及临床安全用药提供科学实验依据。
Nineteen microelements of 12-sided needles from 12 different habitats in Guangxi were analyzed by inductively coupled plasma atomic emission spectrometry (ICP-AES) and atomic fluorescence spectrometry (AFS). The method was characterized by nitric acid-perchloric acid digestion System, effectively and thoroughly digest organic matter in the sample; and for the volatile elemental mercury and selenium, the optimal digestion effect can be achieved by controlling the digestion amount, the digestion temperature and the digestion time of the sample. The method is simple, efficient, with less dosage and accurate results. The spiked recoveries are 90.12% -104.14% and the precision are less than 3%. The results showed that the contents of trace elements in the roots of Zanthoxylum nitidum from different areas were different. The contents of essential trace elements Na, Mg, K, Ca, Zn, The Hg in 12 producing areas and Pb in 11 producing areas all met the standards of medicinal and export, but the content of Cd exceeded the standard of medicine and export. The results provide effective data for studying the correlation between trace elements and pharmacodynamics of two-sided needles, and provide scientific experimental basis for the selection of standardized planting bases and the clinical safety of two-sided needles.