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本文从生物化学角度,介绍了近几年来国外所报道的有关甲基汞对神经系统酶活性的影响、甲基汞对神经系统中神经介质的影响,甲基汞对神经系统蛋白质合成的影响等毒理研究。文章指出,关于甲基汞对神经系统毒性作用的机理有如下假说:甲基汞对神经系统毒性作用的原发部位可能是细胞膜,甲基汞借助于其亲脂特性,与细胞膜上的-SH基结合,损害了细胞膜的通透性,影响线粒体的功能,抑制了蛋白质的
This article from the biochemical point of view, introduced in recent years abroad reported on the methylmercury on the activity of the nervous system enzyme, methylmercury on the nervous system in the nervous mediator, methylmercury on the nervous system protein synthesis effects Toxicological research. The paper points out that the mechanism of methylmercury on the toxic effects of the nervous system has the following hypothesis: methylmercury primary role in the nervous system may be the role of the cell membrane, methylmercury by virtue of its lipophilic properties, and the cell membrane - SH Binding, impairing cell membrane permeability, affecting mitochondrial function, inhibiting protein