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基于目前对黑色素瘤进行选择性淋巴结切除(ELND)的价值仍有争议,一此已发表的前瞻及回顾性文章均持否定意见。悉尼黑色素瘤治疗小组(SMU)收集1960～1991年30年间11000例不同阶段黑色素瘤病人的资料。并从中选择合适的病例进回顾性研究。选择病例的标准是:原发性躯干和四肢的皮肤黑色素瘤,肿瘤厚度在1.5mm以上,无临床淋巴结受累表现,在确诊后60天内行肿瘤广泛切除手术,与此同时,对一部分病人进行ELND,对这些病人至少随访58个月,最长105个月。 1278例病人符合选择标准,其中845例病人进行了ELND,831例的淋巴结可用作病理检查。病理结
The current value of selective lymph node dissection (ELND) for melanoma is still controversial, and both published and retrospective articles have been negative. The Sydney Melanoma Treatment Group (SMU) collected data on 11,000 patients with melanoma at different stages during the 30s from 1960 to 1991. And select suitable cases from the retrospective study. The criteria for selecting patients were primary melanoma of the trunk and extremities, tumor thickness 1.5 mm or more, no clinical lymph node involvement, extensive resection of the tumor within 60 days after diagnosis, and ELND for a subset of patients. These patients were followed up for at least 58 months and up to 105 months. 1278 patients met the selection criteria, among whom 845 patients had ELND and 831 lymph nodes were available for pathological examination. Pathological knot