目的 :研究以强直症状为主的帕金森病 (PD)患者运动皮质的兴奋性是否增高。方法 :选取一组以强直症状为主的PD患者与一组年龄、性别匹配的正常人对照 ,分别测定其静息、易化状态时的运动诱发电位的阈值 ,并进行比较。结果 :以强直症状为主的帕金森病患者运动诱发电位阈值较正常组为低 ,并且没有明显的易化现象。结论 :以强直症状为主的帕金森病患者运动皮质的兴奋性增高 OBJECTIVE: To investigate whether the excitability of motor cortex is increased in Parkinson’s disease (PD) patients with predominantly tetanic symptoms. Methods: A group of patients with PD predominantly characterized by ankylosing spondylosis and a group of age-matched and normal-sex controls were selected and their thresholds for exercise-induced potentials at resting and facilitated states were determined and compared. Results: Parkinson’s disease predominantly characterized by tetanic symptoms was lower in motor evoked potentials than in normal controls, with no obvious facilitation. CONCLUSIONS: Parkinson’s disease, predominantly tetanic, is associated with increased motor cortex excitability