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收集子宫内膜疾患27例,第一组为子宫内膜囊性增殖5例,第二组为子宫内膜不典型增殖5例,第三、四组分别为子宫内膜腺癌2例及子宫内膜间质肉瘤5例。以流式细胞术测定上述四种疾患DNA指数、细胞周期分布及细胞分裂增殖指数。经统计学处理,证实DNA指数第一组与第二、三、四组相比P值<0.05、0.01、0.01。细胞周期分布中,S期百分率:第一组与第四组相比,P值<0.01。结果表明子宫内膜各组疾患的DNA指数比S期百分率更有显著差异,有助于对临界病变进展的预测及预后的估价。
Endometrial disease was collected in 27 cases. The first group included 5 cases of endometrial cystic proliferation, the second group included 5 cases of endometrial atypical proliferation, and the third and fourth groups included endometrial adenocarcinoma in 2 cases and uterus. Endometrial stromal sarcoma in 5 cases. The flow cytometry was used to determine the DNA index, cell cycle distribution, and cell division proliferation index of the above four disorders. After statistical analysis, it was confirmed that the P value of the first group of the DNA index was lower than that of the second group, the third group, and the fourth group (<0.05, 0.01, and 0.01). In the cell cycle distribution, the percentage of S phase: the first group compared with the fourth group, P value < 0.01. The results showed that the DNA index of each group of endometrial lesions was significantly different from the S-phase percentage, which was helpful for the prediction of the progress of critical diseases and the evaluation of the prognosis.