【摘 要】
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To the Editor:rnExtensive liver resection represents a life-saving intervention in patients with primary or secondary liver tumors. Recent ad- vances made in the field of chemotherapy and surgical techniques have translated into a greater number of patien
【机 构】
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“Carol Davila”University of Medicine and Pharmacy,Bucharest 020021,Romania;Department of Anesthesia
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To the Editor:rnExtensive liver resection represents a life-saving intervention in patients with primary or secondary liver tumors. Recent ad- vances made in the field of chemotherapy and surgical techniques have translated into a greater number of patients who are older and with more complex comorbidities presenting for major liver surgery [1] and thus having an increased risk of perioperative mor- tality. Of those, posthepatectomy liver failure (PHLF) represents a life-threatening complication of liver surgery and one of the most important causes of perioperative mortality. The incidence reported in current literature varies between 4.9％ and 32％ [ 2 , 3 ]. Such patients need to be managed by a multidisciplinary team in a dedicated intensive care unit to minimize multi-organ dysfunction associated with PHLF [4] . We hypothesized that lactate dynamics in the setting of liver surgery can be used as a marker of poor liver function. This study aimed to assess the correlation between lactate levels, lactate kinetics and postoperative PHLF in the peri- operative period of major hepatic surgery.
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