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利用抗雌激素受体（ＥＲ）和孕激素受体（ＰＲ）的两种单克隆抗体对３１例卵巢上皮性肿瘤新鲜冰冻标本进行ＡＢＣ法测定，ＥＲ、ＰＲ的阳性表达率分别为４５．２％和４８．４％，恶性肿瘤ＥＲ的含量高于良性者，ＰＲ在良、恶性肿瘤间未见有明显差异。提示：部分卵巢上皮性肿瘤属于激素依赖性肿瘤，对晚期卵巢癌可试用激素疗法。ＥＲ、ＰＲ在宫内膜样癌和浆液性癌的含量高于其它类型上皮性肿瘤，高分化者受体阳性率及含量高于低分化者；ＥＲ或ＰＲＦ阳性者预后好于阴性者，二者具独立的预后因素，且ＥＲ、ＰＲ双阳性者预后比ＥＲ阳性、ＰＲ阴性或ＥＲ阴性、ＰＲ阳性者好。
The positive expression rates of ER and PR in fresh frozen specimens of 31 patients with epithelial ovarian cancer were determined by two kinds of monoclonal antibodies against estrogen receptor (ER) and progesterone receptor (PR). The positive rates of ER and PR were 45.2 % And 48.4% respectively. The content of ER in malignant tumors was higher than that in benign ones. There was no significant difference in PR between benign and malignant tumors. Tip: Some ovarian epithelial tumors are hormone-dependent tumors, advanced ovarian cancer can try hormone therapy. ER, PR in endometrial carcinomas and serous carcinomas than other types of epithelial tumors, well-differentiated receptor positive rate and content were higher than poorly differentiated; ER or PRF positive prognosis is better than negative, two With independent prognostic factors, and ER, PR double positive prognosis than ER positive, PR negative or ER negative, PR positive good.