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作者调查了107例急性肺炎,包括格鲁布性肺炎14例,局灶性肺炎83例。其中男68、女39例,年龄16～70岁。在入院后不同时间即入院时、经治疗2周以后及出院前检测止血指标,包括纤维蛋白原降解产物(FDP)含量、纤维蛋白原浓度,凝血酶原指数、血小板聚集功能。并以17～44岁的健康人作对照。结果表明,全部患者在肺炎极期时,血中FDP量、血小板聚集功能等项指标均显著高于正常值,凝血酶原指数及血管上皮细胞抗聚集活性均较正常值低并有统计学意义,经一般综合治疗以后血中FDP含量较治疗前显著降低(p<0.05),但未达正常水平,并发现FDP值取决于疾病的严重程度,例如病情呈中
The authors investigated 107 cases of acute pneumonia, including Gruber’s pneumonia in 14 cases and focal pneumonia in 83 cases. Male 68, female 39 cases, aged 16 to 70 years. At admission at different times after admission, hemostatic indexes including fibrinogen degradation product (FDP), fibrinogen concentration, prothrombin index, and platelet aggregation were measured after 2 weeks of treatment and before discharge. And 17 to 44-year-old healthy people as a control. The results showed that all the patients in the extreme period of pneumonia, the amount of blood FDP, platelet aggregation and other indicators were significantly higher than normal, prothrombin index and anti-agglutination of vascular epithelial cells were lower than normal and statistically significant , After the general treatment of blood FDP levels were significantly lower than before treatment (p <0.05), but not up to normal levels, and found that the FDP value depends on the severity of the disease, such as the condition was