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目的:了解广州市2005年-2009年从业人员乙型肝炎病毒(HBV)的感染状况,为制定防控措施提供科学依据。方法:用ELISA法检测乙肝病毒表面抗原(HBsAg)、乙肝病毒e抗原(HBeAg)。结果:2005年-2009年从业人员的HBsAg平均阳性率为5.01%(52748/1052570),HBeAg平均阳性率为1.50%(15758/1052570),HBeAg阳性人数占HB-sAg阳性人数的平均百分比为29.87%(15758/52748);HBsAg、HBeAg的阳性率呈逐年下降趋势;年龄组中30～岁组检出HBsAg阳性率最高(5.40%),检出HBeAg阳性率最高的是<30岁组(1.86%),不同年龄组间的HBsAg、HBeAg阳性检出率的差异有统计学意义(P<0.001),HBeAg阳性率随着年龄的增长而下降;男性的HBsAg、HBeAg阳性率比女性高,差异有统计学意义(P<0.001)。结论:广州市从业人员HBV感染状况呈逐年下降趋势。通过全民健康教育、健康促进,接种疫苗等措施可减少HBV感染。
Objective: To understand the status of hepatitis B virus (HBV) infection among practitioners in Guangzhou from 2005 to 2009, and provide a scientific basis for the development of prevention and control measures. Methods: The hepatitis B virus surface antigen (HBsAg) and hepatitis B virus e antigen (HBeAg) were detected by ELISA. Results: The average positive rate of HBsAg between 2005 and 2009 was 5.01% (52748/1052570), the average positive rate of HBeAg was 1.50% (15758/1052570), the average percentage of HBeAg positive persons who took HB-sAg positive was 29.87 % (15758/52748). The positive rate of HBsAg and HBeAg showed a declining trend year by year. The positive rate of HBsAg was the highest in the age group of 30 ~ 5.40%, the highest rate of HBeAg was in the age group of 30 %). The positive rates of HBsAg and HBeAg in different age groups were significantly different (P <0.001), and the positive rates of HBeAg decreased with the growth of age. The positive rates of HBsAg and HBeAg in males were higher than those in females There was statistical significance (P <0.001). Conclusion: The prevalence of HBV infection among practitioners in Guangzhou shows a declining trend year by year. Through universal health education, health promotion, vaccination and other measures can reduce HBV infection.