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众所周知,卡马西平(CBZ)除抗惊厥作用外,还用于治疗三叉神经痛和舌咽神经痛等神经痛疾病,其衍生物奥卡西平(OXCBZ)因副作用较少和疗效类似,也被用来治疗神经性痛,但其镇痛作用的机制至今不明。贝尔格莱德大学的Vuckovic等人在大鼠炎性痛模型中对肾上腺素α2受体参与卡马西平和?
As we all know, carbamazepine (CBZ) in addition to the role of anticonvulsant, but also for the treatment of neuralgia and other diseases of the trigeminal neuralgia and glossopharyngeal neuralgia, its derivatives oxcarbazepine (OXCBZ) due to less side effects and similar effects were also The mechanism used to treat neuropathic pain but its analgesic effect remains unknown. Vuckovic et al at the University of Belgrade are involved in carbamazepine on adrenergic α2 receptors in a rat model of inflammatory pain.