目的研究采用三维适形放疗法治疗食管癌的效果与不良反应。方法选取笔者所在科室收治的64例食管癌患者临床资料进行回顾分析,随机将患者分为观察组(行三维适形放疗法)与对照组(常规三野照射疗法),综合评价两组放疗方法的临床疗效与不良反应。结果经临床放射治疗,观察组有效率为100%,高于对照组的84.38%,差异有统计学意义(P<0.05);均出现I-Ⅲ级的气管反应、骨髓抑制、胃肠道反应、食管黏膜反应、皮肤反应,但不良反应无统计学差异(P>0.05),均经对症治疗后消失。结论在治疗食管癌疾病中采用三维适形放疗不仅能够显著改善临床疗效,同时还有不良反应率、并发症少、恢复快等优点,值得临床推广应用。 Objective To study the efficacy and adverse reactions of three-dimensional conformal radiotherapy in the treatment of esophageal cancer. Methods The clinical data of 64 patients with esophageal cancer treated in our department were retrospectively analyzed. Patients were randomly divided into observation group (three-dimensional conformal radiotherapy) and control group (conventional three-field radiation therapy), and the comprehensive evaluation of two groups of radiotherapy methods Clinical efficacy and adverse reactions. Results The effective rate of the observation group was 100%, which was higher than that of the control group (84.38%) by clinical radiotherapy, the difference was statistically significant (P <0.05); there were tracheal reaction, myelosuppression, gastrointestinal reaction , Esophageal mucosa reaction and skin reaction, but there was no significant difference in adverse reactions (P> 0.05), all disappeared after symptomatic treatment. Conclusion Three-dimensional conformal radiotherapy in the treatment of esophageal cancer can not only improve the clinical curative effect, but also have the advantages of less adverse reaction rate, less complications and faster recovery, which is worthy of clinical application.