在脊椎动物的进化过程中,自然妊娠的成功仍是一个大谜。多年来,把滋养层细胞表面可能缺乏主要组织相容性复合体(MHC)抗原,作为解释妊娠成功的最有说服力的假说。但是,对人和小鼠的滋养层细胞进行了大量研究,结果引起了激烈的争论。为了重新审查这些结果,作者使用了具有高度敏感性和特异性的技术,对人和小鼠 The success of natural pregnancy remains a mystery in the evolution of vertebrates. Over the years, the trophoblast cell surface may lack the major histocompatibility complex (MHC) antigen as the most convincing hypothesis to explain the success of pregnancy. However, a large number of studies have been conducted on trophoblast cells in humans and mice, and the results have caused heated debate. In order to re-examine these results, the authors used a highly sensitive and specific technique for human and mouse