间日疟原虫(Plasmodium vivax)红细胞内期的形态异常,国外早有报道。国内自60年代江静波等(1961,1965)对广东的间日疟形态进行了系统的观察以来,河南(1965,1982),广西,安徽淮南(1981)和山东(1982)等地都先后发现间日疟原虫的异常形态、重复感染及不同期混合感染。1982年7～9月,我们在安徽省淮北市验证5-对氟苯氧基伯喹柠檬酸盐对间日疟患者的毒副反应时,在收治的139例间日疟患者中,也发现6例原虫形态与经典描述 Plasmodium vivax erythrocyte phase morphology abnormalities, foreign reports have long been reported. Since the 1960s, Jiang Jingbo et al. (1961, 1965) systematically observed the forms of Plasmodium vivax in Guangdong Province, Henan (1965,1982), Guangxi, Anhui Huainan (1981) and Shandong (1982) Plasmodium vivax abnormal morphology, repeated infections and mixed infection at different stages. From July to September 1982, when we tested the toxic side effects of 5-p-fluorophenoxyquine citrate on vivax malaria patients in Huaibei City of Anhui Province, among the 139 patients with vivaxumab 6 cases of protozoan morphology and the classic description