目的:了解道真自治县围产儿出生缺陷的发生状况及影响因素,为制定有效的干预措施提供依据。方法:对2003～2008年间监测医院住院分娩的围产儿出生缺陷病例进行分析。结果:道真自治县出生缺陷发生率高,出生缺陷以神经管畸形为主,出生缺陷的发生与多种因素有关。结论:加大健康教育力度,普及优生优育知识,提倡婚前保健,加强孕前保健和孕期保健工作以及产前筛查和产前诊断是降低出生缺陷的有效措施。 Objective: To understand the occurrence and influencing factors of birth defects in perinatal children in Daozhen Autonomous County, and to provide the basis for making effective interventions. Methods: The incidence of perinatal birth defects in hospitals monitored during 2003 ~ 2008 were analyzed. Results: The incidence of birth defects in Daozheng Autonomous County was high. The birth defects were mainly neural tube defects. The incidence of birth defects was related to many factors. Conclusion: It is an effective measure to reduce birth defects by increasing health education, popularizing knowledge of prenatal and postnatal care, promoting prenuptial care, strengthening prenatal care and pregnancy health care, and prenatal screening and prenatal diagnosis.